Hacienda Enriqueta was established in 1884 by German immigrant Heinrich Kleibring Geldmeier (1830-1890) who named it in honor of his daughter Enriqueta Kleibring Sotomayor (1869-1914). Kleibring installed a steam powered mill acquired from the defunct Hacienda Nueva Esperanza property of Ramón López. 

Enriqueta inherited the property and after her death in 1914, her widower Tomás Antero Babilonia Talavera (1859-1933) continued to work the hacienda.  In 1925, Tomás sold the hacienda to Alberto Esteves Volkers (1891-1969) and his wife Juan Sofia Marqués Seín (1897-1974).  Volkers continued to plant sugarcane which was then processed at Central Coloso. 

It is reported that the property is currently owned by Dr. Eleuterio (Tellito) Loperena Jimenez who converted it into museum.